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Hormone Therapy for Breast Cancer

Hormonal therapy for breast cancer, is the treatment for breast cancer that is sensitive to hormones. Receptor-Negative Breast Cancers

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Hormonal therapy for breast cancer, is the treatment for breast cancer that is sensitive to hormones. It's recommended for women with hormone receptor-positive breast cancers, this therapy does not work who have receptor-negative breast cancers. Hormone therapy is a form of systematic therapy it reaches to cancer anywhere in the body.

Other than the hormone therapy, the hormonal receptor-positive breast cancers treated in two ways:

  • Lower the amount of the hormone estrogen in the body.
  • Close the action of estrogen on breast cancer cells.

Most of the estrogen in women's body is made by ovaries, estrogen makes hormone-receptor-positive breast cancers grow. So, reducing the amount of estrogen by lowering the amount or by closing the action can help reduce the risk of early-stage hormone-receptor-positive breast cancers or cancer recurrence. This therapy is also used to shrink the growth of advanced-stage or hormone-receptor-positive breast cancers.

Hormones are known as a chemical messenger in the human body. They are produced in the endocrine glands, which includes:

Hormone Therapy

  • for Women - thyroid, pancreas, ovaries in women.
  • for Men - testes.

While in some cases hormones in the body encourages cancer cell to grow, where in other cases they may kill, slow or stop the cancer cell.

Hormonal therapy involves drug(medication) to prevent cancer from getting the hormones they need to grow. Sometimes, your doctor may suggest combining the hormonal therapy with other therapies such as chemotherapy, and radiation therapy. In some cases, your doctor will surgically remove the gland which regenerates the hormone production.

Why hormone therapy

Hormone therapy with caner is only used to treat cancer which are hormone-sensitive means hormone receptor-positive breast cancers. Doctor refers to this as PR positive or ER-positive, this means the breast cancers are fueled by the natural hormones’ estrogen or progesterone. The doctor will determine if your cancer is PR positive or ER-positive by examine the cancer cells to see if they have receptors for estrogen or progesterone.

Hormone therapy for breast cancer will help:

  • Prevent recurrence of cancer.
  • It will decrease the risk of cancer developing in other breast tissue.
  • It will slow down or stop the growth of cancer that has spread.
  • Reduce the size of a tumor before surgery.

Risks of Hormone therapy

Some of the side effects of hormone therapy for breast cancer include:

  • Hot flashes.
  • Vaginal discharge.
  • Vaginal dryness.
  • Fatigue.
  • Nausea.
  • Joint and muscle pain.

Hormone Therapy for breast cancer

More serious side effects may include:

  • Blood clots in veins.
  • Endometrial cancer.
  • uterine cancer.
  • Cataracts.
  • Stroke.
  • Osteoporosis.
  • Heart disease.

Less common types of hormone therapy

  • Megestrol acetate (Megace), a progesterone-like drug.
  • Androgens (male hormones).
  • High doses of estrogen.


Magnus Medi blogs are purely meant for information purpose. It contains only general information and discussions about health and its related subjects. It is not a medical advice and should not treat as such. The words and other content provided in this blog, and in any linked materials, are not intended and should not be construed as medical advice. The opinions and views expressed on this blog are referred by a healthcare site and from experienced medical practitioners.

If the reader or any other person has a medical concern, you should consult with your health care provider or seek other professional medical treatment. Never disregard professional medical advice or delay seeking it. Or you can contact us our executive will help you get the second opinion from renowned doctors.

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